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Identification and Strategies to Mitigate High Total Clearance of Benzylamine-Substituted Biphenyl Ring Systems

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Beth WILLIAMSON, Project rep, Doctor of Philosophy, AstraZeneca, London, AZ, Drug Metabolism & Pharmacokinetics (DMPK)

PDF) Predicting when Biliary Excretion of Parent Drug is a Major Route of Elimination in Humans

Christina CHAN, Researcher, PhD, AstraZeneca, London, AZ, Drug Metabolism & Pharmacokinetics (DMPK)

Metabolism by Aldehyde Oxidase: Drug Design and Complementary Approaches to Challenges in Drug Discovery

Identification and Strategies to Mitigate High Total Clearance of Benzylamine-Substituted Biphenyl Ring Systems

Synthetic Approaches to New Drugs Approved during 2018

Scott Boyd's research works AstraZeneca, London (AZ) and other places

Identification and Strategies to Mitigate High Total Clearance of Benzylamine-Substituted Biphenyl Ring Systems

Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach